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- Using genetics, researchers identify potential drugs for early treatment of COVID-19
- Antibody binding-site conserved across COVID-19 virus variants
- Aluminum is intricately associated with the neuropathology of familial Alzheimer's disease
- Interleukin-33 involved in immunity to Sars-CoV-2
- Sunlight linked with lower COVID-19 deaths, study shows
- Leaking calcium in neurons an early sign of Alzheimer's pathology
| Using genetics, researchers identify potential drugs for early treatment of COVID-19 Posted: 09 Apr 2021 09:47 AM PDT A new study using human genetics suggests researchers should prioritize clinical trials of drugs that target two proteins to manage COVID-19 in its early stages. Based on their analyses, the researchers call for prioritizing clinical trials of drugs targeting the proteins IFNAR2 and ACE2. The goal is to identify existing drugs, either FDA-approved or in clinical development for other conditions, that can be repurposed for the early management of COVID-19. |
| Antibody binding-site conserved across COVID-19 virus variants Posted: 09 Apr 2021 09:47 AM PDT A tiny protein of SARS-CoV-2, the coronavirus that gives rise to COVID-19, may have big implications for future treatments, according to a team of Penn State researchers. |
| Aluminum is intricately associated with the neuropathology of familial Alzheimer's disease Posted: 09 Apr 2021 09:47 AM PDT A new study continues to support a growing body of evidence that aluminum contributes to the pathogenesis of Alzheimer's disease (AD). Researchers found aluminum co-located with phosphorylated tau protein, which is an early initiator of AD. |
| Interleukin-33 involved in immunity to Sars-CoV-2 Posted: 09 Apr 2021 07:44 AM PDT A new study reveals the involvement of interleukin-33, an important alarm signal, when immune cells get exposed to Sars-CoV-2 for a second time. |
| Sunlight linked with lower COVID-19 deaths, study shows Posted: 08 Apr 2021 06:29 PM PDT Sunnier areas are associated with fewer deaths from COVID-19, an observational study suggests. Increased exposure to the sun's rays -- specifically UVA -- could act as a simple public health intervention if further research establishes it causes a reduction in mortality rates, experts say. |
| Leaking calcium in neurons an early sign of Alzheimer's pathology Posted: 08 Apr 2021 12:23 PM PDT Alzheimer's disease is known for its slow attack on neurons crucial to memory and cognition. But why are these particular neurons in aging brains so susceptible to the disease's ravages, while others remain resilient? |
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