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Direct cloning method CAPTUREs novel microbial natural products

Posted: 19 Feb 2021 04:09 PM PST

Microorganisms possess natural product biosynthetic gene clusters (BGCs) that may harbor unique bioactivities for use in drug development and agricultural applications. However, many uncharacterized microbial BGCs remain inaccessible. Researchers previously demonstrated a technique using transcription factor decoys to activate large, silent BGCs in bacteria to aid in natural product discovery.

Depression, anxiety, loneliness are peaking in college students

Posted: 19 Feb 2021 04:09 PM PST

New nationwide survey data uncovers college students' current mental health challenges and needs.